Bioidentical Hormone Replacement Therapy Research Articles

Bioidentical hormone replacement therapy (BHRT) is a fascinating field of medicine with enormous amounts of research devoted to it. We have pulled together relevant BHRT articles for those who are interested in a deeper review. The list of scientific studies will help you gain additional insight into the ongoing research and its implications.

Fundamental Concepts Regarding Testosterone Deficiency and Treatment: International Expert Consensus Resolutions

PUBLISHED by Mayo Clinic Proceedings, Diagnosis and Treatment Guidelines, 2016.    AUTHORS: Abraham Morgentaler, MD (Chairman); Michael Zitzmann, MD (Cochairman); Abdulmaged M. Traish, PhD (writing group); Anthony W. Fox, MSc, MD (writing group); T. Hugh Jones, MD (writing group); Mario Maggi, MD (writing group); Stefan Arver, MD; Antonio Aversa, MD; Juliana C.N. Chan, MD; Adrian S. Dobs, MD; Geoffrey I. Hackett, MD; Wayne J. Hellstrom, MD; Peter Lim, MD; Bruno Lunenfeld, MD; George Mskhalaya, MD; Claude C. Schulman, MD; and Luiz O. Torres, MD

An international panel of experts met in October 2015 in an attempt to put together a group of consensus statements on the benefits and safety of testosterone therapy. Following the summit, the panel made 9 resolutions. The abstract clearly defines these 9 resolutions. (1) Testosterone (T) Deficiency (TD) is a well-established, clinically significant medical condition that negatively affects male sexuality, reproduction, general health, and quality of life; (2) symptoms and signs of TD occur as a result of low levels of T and may benefit from treatment regardless of whether there is an identified underlying etiology; (3) TD is a global public health concern; (4) T therapy for men with TD is effective, rational, and evidence based; (5) there is no T concentration threshold that reliably distinguishes those who will respond to treatment from those who will not; (6) there is no scientific basis for any agespecific recommendations against the use of T therapy in men; (7) the evidence does not support increased risks of cardiovascular events with T therapy; (8) the evidence does not support increased risk of prostate cancer with T therapy; and (9) the evidence supports a major research initiative to explore possible benefits of T therapy for cardiometabolic disease, including diabetes. These resolutions may be considered points of agreement by a broad range of experts based on the best available scientific evidence.

Misperceptions of Testosterone Replacement Therapy and Heart Disease Risk (video)

RECORDED in Madrid, Spain, at the annual meeting of the European Association of Urology (EAU), March 2015.    AUTHORS: Dr. Abraham Morgentaler

The Mortality Toll of Estrogen Avoidance: An Analysis of Excess Deaths Among Hysterectomized Women Aged 50 to 59 Years

PUBLISHED on American Journal of Public Health, February 2013.   AUTHORS: Philip M. Sarrel MD, Valentine Y. Njike MD MPH, Valentina Vinante MD, David L. Katz MD MPH

No VTE Risk Seen With Testosterone Therapy

PUBLISHED on MedPage and Mayo Clinic Proceedings, July 2015.   AUTHORS Jacques Baillargeon, PhD, Randall J. Urban, MD, Abraham Morgentaler, MD, Charles J. Glueck, MD, Gwen Baillargeon, MS, Gulshan Sharma, MD, MPH, Yong-Fang Kuo, PhD

Estrogen Replacement Therapy in Breast Cancer Survivors: a Matched-Controlled Series

PUBLISHED on Menopause – The Journal of the North American Menopause Society, July 2003, Volume 10, Issue 4, pp 277-285.   AUTHORS Decker, David A. MD; Pettinga, Jane E. MD; VanderVelde, Nancy MD; Huang, Raywin R. PhD; Kestin, Larry MD; Burdakin, John H. MD

Estrogen Replacement Therapy After Breast Cancer: A 12-Year Follow-Up

PUBLISHED on Annals of Surgical Oncology, Dec 2001, Volume 8, Issue 10, pp 828-832.   AUTHORS George N. Peters MD, Tomasina Fodera MD, Jennifer Sabol MD, Stephen Jones MD, David Euhus MD

Study Finds No Convincing Evidence of Increased Cardiovascular Risk with Testosterone Therapy

PUBLISHED on HCPLive Resources, 2015.   AUTHORS Andrew Smith.

Testosterone Therapy and Cardiovascular Risk: Advances and Controversies

PUBLISHED on Mayo Clinic Proceedings,, 2015.   AUTHORS Abraham Morgentaler, MD, Martin M. Miner, MD, Monica Caliber, MSc, Andre T. Guay, MD, Mohit Khera, MD, Abdulmaged M. Traish, PhD.

Research on Benefits and Risks of Testosterone Replacement Affected by Poorly Done Studies

PUBLISHED on Wiley Online Library by AlphaMed Press, 2014.   AUTHORS Jo CH, Lee YG, Shin WH, Kim H, Chai JW, Jeong EC, Kim JE, Shim H, Shin JS, Shin IS, Ra JC, Oh S, Yoon KS.

Testosterone Therapy May Lower Risk of Heart Disease

PUBLISHED on RTT News, 2013.

Early Initiation of HRT ‘Halves Risk of Death or CVD’

PUBLISHED on Pulse – Atthe Heart of General Practice, 2012   AUTHORS David Swan

Testosterone Keeps Women’s Brains Sharp

PUBLISHED on MedPage Today, 2013.   AUTHORS Todd Neale

Testosterone Therapy May Improve Sexual Function for Women

PUBLISHED on, 2013.

Estrogen Is a New Weapon Against Urinary Tract Infection in Post Menopausal Woman

PUBLISHED on Science Daily, 2013.   AUTHORS Karolinska Institutet

Estrogen Can Reduce Risk of Liver and Heart Disease in Women

PUBLISHED on BioOptics World, 2013.   AUTHORS Lee Mather

Estrogen Replacement Therapy May Save Lives After All

 PUBLISHED on Forbes, 2013.   AUTHORS Alice Walton

Testosterone Therapy Does Not Hike Risk of Aggressive Prostate Cancer

PUBLISHED on Renal and Urology News, 2013.   AUTHORS Jody Charnow

Hormone Therapy Makes Menopause Easier

PUBLISHED on Get Healthy by The Times, 2013.

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